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“Medicinal amount”

The verified answer to the Newsday Crossword clue “Medicinal amount”, with letter-by-letter analysis and the full puzzle context for the Wednesday, December 24, 2025 puzzle.

Published · Down · 4 letters

Hints first

Letters 4
First letter D
Last letter E
D ? ? E

A 4-letter down entry from the Wednesday puzzle

The Answer

D O S E

The answer to “Medicinal amount” is DOSE

Letters 4
Direction Down
Published Dec 24, 2025

Letter analysis: the 4-letter answer

Vowels, consonants, and crossword construction notes
Unique 4 of 4 positions
Vowels 2 50% of word
Consonants 2 non-vowels
First letter D starts with

The clue “Medicinal amount” appeared in the Newsday Crossword on Wednesday, December 24, 2025 as a down entry. The verified answer is DOSE — a 4-letter word that begins with D and ends with E.

This answer contains 2 vowels and 2 consonants. The Newsday Crossword is published daily by Newsday on Long Island and edited by Stan Newman, whose Saturday Stumper is widely considered one of the toughest mainstream crosswords in print.

Other clues with the answer DOSE

DOSE has been used as the answer for these Newsday Crossword clues
“Medicine portion” May 19, 2026 “Amount of medicine to take” May 4, 2026 “Medicine portion” Jan 27, 2026 “Amount of medicine to take” Nov 11, 2025 “Portion of medicine” Mar 4, 2025 “Portion of medicine” Jan 14, 2025

More clues from the December 24, 2025 puzzle

Wednesday Newsday Crossword
View full puzzle
See 43-Down 4 ℓ · D Ripened, as cheese 4 ℓ · D Ginger ale, for instance 4 ℓ · D Spout lava 5 ℓ · D Turned loose 5 ℓ · D Mountains of France 4 ℓ · A C sharp alas 5 ℓ · A In addition 4 ℓ · D ONE OF THE OCTET 6 ℓ · D Cribs, cots, etc. 4 ℓ · A Profs.' helpers 3 ℓ · D Impolite glance 4 ℓ · D Wide belt 4 ℓ · D The Dalai __ 4 ℓ · D Take out a loan 6 ℓ · D In addition 3 ℓ · D Snatch forcibly 5 ℓ · A With 49- and 7-Down, what the octet are 6 ℓ · D Risk taking, for short 4 ℓ · A NASA's six-person orbiter: Abbr. 3 ℓ · A

Frequently asked questions about “Medicinal amount”

What is the answer to “Medicinal amount” in the Newsday Crossword?

The verified answer is DOSE — a 4-letter word that appeared as a down entry on Wednesday, December 24, 2025.

How many letters is the answer to “Medicinal amount”?

The answer DOSE contains 4 letters.

Was “Medicinal amount” an across or down clue?

This clue ran as a Down entry.

Is this site affiliated with Newsday?

No. This is an independent fan reference site — we are not affiliated with Newsday. The Newsday Crossword is a trademark of its respective owner. We solve and verify each Newsday Crossword puzzle manually before publishing the answer key.

Medicinal amount — Newsday Crossword Clue Answer | Newsday Crossword Answers