“Brother of Isaac”

The verified answer to the Newsday Crossword clue “Brother of Isaac”, with letter-by-letter analysis and the full puzzle context for the Wednesday, September 23, 2026 puzzle.

Hints first

Letters 4
First letter E
Last letter U
E ? ? U

A 4-letter across entry from the Wednesday puzzle

The Answer

E S A U

The answer to “Brother of Isaac” is ESAU

Letters 4
Direction Across
Published Sep 23, 2026

Letter analysis: the 4-letter answer

Vowels, consonants, and crossword construction notes
Unique 4 of 4 positions
Vowels 3 75% of word
Consonants 1 non-vowels
First letter E starts with

The clue “Brother of Isaac” appeared in the Newsday Crossword on Wednesday, September 23, 2026 as a across entry. The verified answer is ESAU — a 4-letter word that begins with E and ends with U.

This answer contains 3 vowels and 1 consonant. The Newsday Crossword is published daily by Newsday on Long Island and edited by Stan Newman, whose Saturday Stumper is widely considered one of the toughest mainstream crosswords in print.

Other clues with the answer ESAU

ESAU has been used as the answer for these Newsday Crossword clues

More clues from the September 23, 2026 puzzle

Wednesday Newsday Crossword
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Frequently asked questions about “Brother of Isaac”

What is the answer to “Brother of Isaac” in the Newsday Crossword?

The verified answer is ESAU — a 4-letter word that appeared as a across entry on Wednesday, September 23, 2026.

How many letters is the answer to “Brother of Isaac”?

The answer ESAU contains 4 letters.

Was “Brother of Isaac” an across or down clue?

This clue ran as a Across entry.

Is this site affiliated with Newsday?

No. This is an independent fan reference site — we are not affiliated with Newsday. The Newsday Crossword is a trademark of its respective owner. We solve and verify each Newsday Crossword puzzle manually before publishing the answer key.

Brother of Isaac — Newsday Crossword Clue Answer | Newsday Crossword Answers